A non-flammable, low-GWP HFO refrigerant used in large centrifugal chillers as a replacement for high-GWP refrigerants such as R-123 and R-245fa. It operates at low pressures similar to R-123 and has a GWP below 5.
HVAC Glossary
R-1233zd(E)
Last updated: June 9, 2026